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On the other hand, another pro-inflammatory cytokine is IL-8, which has numerous activities such as the migration of neutrophils, monocytes, tumor cell proliferation, and metastasis [32, 39]

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Conditions such as malnutrition, alcoholism, certain medical conditions (e.g., Crohns disease, celiac disease), or restrictive diets (e.g., veganism without adequate supplementation for *B12*) can lead to deficiencies in one or more of these crucial vitamins

Vittone J, Blackman MR, Busby-Whitehead J, Tsiao C, Stewart KJ, Tobin J, Stevens T, Bellantoni MF, Rogers MA, Baumann G, Roth J, Harman SM, Spencer RG