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Many people in these regions are unaware of their HTN and don't receive treatment (Rx)

autonomic sympathetic neurons , brain tissue & and transports monoamines (dopamine, norepinephrine, serotonin & histamine) from the cytoplasm into presynaptic storage vesicles Binds to the same site on VMAT1 & 2 as intracellular monoamines, producing a strong long-lasting inhibition of monoamine (e.g

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Do not give benzodiazepines if only mild symptoms are present (Madsen, 2025)