While these diseases have distinct etiologies and pathologies, they all involve neuronal loss and sustained activation of the brains immune system, including microglia and astrocytes ( A key driver of neuronal injury is oxidative stress, which arises when the generation of reactive oxygen species (ROS) overwhelms the brains antioxidant defenses, one such defense being glutathione (GSH) (Tfilin et al., 2023)
Specifically, the genotype of SMARCA4, ARID1A, PBRM1 or SMARCB1 was determined as the number of altered allele(s) with mutations
However, oxidative stress has been associated with various mental health conditions, so maintaining a good antioxidant status may support overall mental well-being
Self-administration can carry risks such as infection, allergic reactions, improper dosing, pain, bruising, and unexpected side effects