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Based on REDEFINE trial populations and the NDA submission terms, expected eligibility criteria are: BMI 30 , or BMI 27 with at least one weight-related condition such as hypertension, dyslipidemia, type 2 diabetes, or obstructive sleep apnea Adults 18 years or older Not pregnant or breastfeeding Contraindications will likely include: personal or family history of MTC or MEN 2 syndrome, prior serious allergic reaction to semaglutide or cagrilintide, and active pancreatitis

Innate immunity

Results are now negative for hepatitis B e antigen and positive for hepatitis B e antibody

A US Food and Drug Administration advisory committee is scheduled to meet in July 2026 to consider whether pharmacies should be permitted to compound and sell seven unapproved peptides, with BPC-157 among them