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Abstract Head and neck cancer is the sixth most common cancer across the globe

Conclusion: EDB alleviates brain injury and improves outcomes in acute ischemic stroke by regulating astrocytes, inhibiting their activation, and enhancing synaptic connectivity through the neurexin1-neuroligin3 pathway

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This includes: Pernicious anemia Crohns disease or celiac disease Gastric surgery or gastrointestinal disorders For mild deficiency, starting with 1,000 mcg of Vitamin B12 weekly is common