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While large human trials are pending, preclinical and mechanistic evidence is strong

In this review, we aim to revise our current understanding of the mechanisms by which hyperoxia leads to organ damage and to highlight possible areas of investigation for the scientific community interested in novel mechanisms of kidney disease

10.3389/fmicb.2024.1345478 259 SharifK.SharifA.JumahF.OskouianR.TubbsR

Connective tissue diseases include joint hypermobility syndrome, or the hypermobility spectrum disorder, Ehlers-Danlos syndrome, Marfan syndrome, osteogenesis imperfecta, Stickler syndrome