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Downregulation of PCBP1/2 mediates Fe 2+ release and induces ferroptosis To explore the potential mechanism by which ACE elevates Fe 2+ levels, iron metabolism proteins associated with ACE were screened by Western blot based on proteomic results (Fig

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J Neurosci Res 79:6573 Mastorodemos V, Kotzamani D, Zaganas I, Arianoglou G, Latsoudis H, Plaitakis A (2009) Human GLUD1 and GLUD2 glutamate dehydrogenase localize to mitochondria and endoplasmic reticulum