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Oxidative stress controls regulatory T cell apoptosis and suppressor activity and PD-L1-blockade resistance in tumor

Supplements are not regulated by the FDA in the same way as prescription medications, and individual results may vary

One example is nuclear factor-2 (Nrf2), a transcription factor that plays a role in regulating inflammation and cancer prevention by up-regulating the genes that encode for antioxidant and detoxification enzymes like superoxide dismutase (SOD) and glutathione transferase (GST)

however, the studies included in the pooled analysis were too heterogeneous to inform an association (140)