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Graphical abstract Similar content being viewed by others Introduction Age-related macular degeneration (AMD) is a leading cause of vision loss globally, affecting ~ 150 million people in 2020, with that number expected to increase by nearly 50% by 2040 [1, 2]

doi: 10.1111/j.1399-3054.2007.00961.x 3 BelaK.HorvthE.Gall.SzabadosL.TariI.CsiszrJ

Given that ADE has been observed across multiple viral infections, a thought-provoking question arises: if ADE-mediated antibody responses during secondary infections were solely responsible for driving severe disease, why do most of these viruses not consistently lead to more severe illness upon reinfection

The freeze monitor box is equipped with a metal grid for foot shocks and records the animals vertical and horizontal movements