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That $2.65 gap between the Northeast and the South is mostly explained by one variable: how much each state charges in excise taxes

In January 2018, the National Academies of Science, Engineering and Medicine released a consensus report that reviewed over 800 different studies and found that the inhalation of harmful chemicals from e-cigarettes can cause irreversible lung damage and disease

Across disposable e-cigarettes, pre-filled and rechargeable devices, and e-liquids, the study found that average nicotine strength increased the most in disposable e-cigarettes, increasing from 2.1% to 4.8% compared to prefilled pods, which increased from 2.9% to 4.4% and e-liquids, which increased from 1.7% to 2.5%

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