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Ini mengubah eumelanin, pigmen gelap, menjadi pheomelanin, pigmen yang lebih terang

Abeta plaque accumulates in the extracellular space, but Alzheimers is also strongly associated with another misfolded protein, phosphorylated tau

Thus far, approximately 40 companies worldwide, including Codiak Biosciences, Evox Therapeutics, Tavec Pharmaceuticals, Carmine Therapeutics, Anjarium, and Micromedmark Biotech, have developed exosome-based therapies, which are expected to provide cost-effective and more accurate targeted therapies in the clinic ( However, challenges, such as large-scale production, purity, and batch homogeneity of exosomes, still limit their clinical application

Sensitive tests like digital ELISA have been found to be helpful in identifying low-level disease activity and even in pre-dicting imminent flares (240)