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Benjamin Brown has received consultancy fees from Pure Encapsulations (Sudbury, MA, USA)

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Supplementary material The Supplementary Material for this article can be found online at: Abbreviations IL-10, interleukin-10, APAP, acetaminophen, AALF, acetaminophen-induced acute liver failure, AALI, acetaminophen-induced acute liver injury, MDM, monocyte-derived macrophage, PCNA, proliferating cell nuclear antigen, PE, phycoerythrin, SEM, standard error of the mean, ANOVA, analysis of variance, MDSC, myeloid-derived suppressor cell, H&E, hematoxylin and eosin, MODS, multiorgan dysfunction syndrome, NAC, N-acetylcysteine, CARS, compensatory anti-inflammatory response syndrome

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