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Mechanistically, selenium deficiency may exacerbate thyroid-related neurological dysfunction through three pathways: impaired deiodinase activity, weakened antioxidant defense, and disrupted selenium transport (134136)

14 Adults under 50: ~2.4 mcg per day Adults over 50: 2.4 mcg per day Older adults are advised to supplement with B12 where necessary due to the reduced stomach acid and intrinsic factor and/or medications

SOD belongs to a group of metalloenzymes that catalyzes the dismutation of superoxide anion to hydrogen peroxide and molecular oxygen, while Cat decomposes hydrogen peroxide to water and molecular oxygen (50)

Its very short half-life makes it a "natural mimetic" molecule, particularly suited to research protocols on the physiological GH axis