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Originally termed Stein-Leventhal syndrome, PCOS represents a multisystem disorder characterized by intricate associations with metabolic dysregulation and hypothalamic-pituitary-ovarian axis (HPOA) dysfunction, posing substantial threats to fertility during womens prime reproductive years ( PCOS typically manifests during adolescence and is diagnostically characterized by three main features: namely long-term ovulatory dysfunction, hyperandrogenism (HA), and polycystic ovarian morphology, which form the basis of the diagnostic criteria for PCOS (Siddiqui et al., 2022)

In addition to Res, melatonin can improve the functional status of mitochondria by promoting their production via the MT1/SIRT1/PGC-1 signaling pathway, thereby protecting against the hepatotoxicity caused by cadmium exposure [8]

May loosen viscosity and rigidity of the mucus to make it easier to breathe

Ficker, A M