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Patients should be informed of the pros and cons of oral versus parenteral therapy, and regardless of the form of treatment, those with pernicious anemia or malabsorption should be reminded of the need for lifelong replacement

For instance, studies have demonstrated that although NCEH activity was indeed absent in HSL-null adipocytes, a substantial fraction of catecholamine stimulated lipolysis (90, 94), and most, if not all, basal lipolysis remained (30, 134)

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