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10.1038/srep44978

doi: 10.1016/j.jinsphys.2007.04.002 184

The NHS and NICE recommend PDE5 inhibitors (sildenafil, tadalafil, vardenafil, avanafil) as first-line treatment, alongside lifestyle modifications and management of underlying conditions

Cagrilintide is the first long-acting amylin analog to reach Phase 3 trials, with fatty acid acylation enabling once-weekly dosing compared to the three-times-daily dosing required by the older amylin analog pramlintide