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E-Cigarettes May Promote Illicit Drug Use and Addiction Nicotine, no matter the source, may function as a gateway to marijuana and cocaine Like conventional cigarettes, electronic cigarettes (or e-cigarettes) may function as a gateway druga drug that lowers the threshold for addiction to other substances, such as marijuana and cocaineaccording to the 120th Shattuck lecture, presented to the Massachusetts Medical Society by Columbia researchers Denise and Eric Kandel and published today in the online edition of the New England Journal of Medicine