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Nicotine has been shown to improve focus, alertness, and reaction time, which can be beneficial for athletes and others who need to be at the top of their game

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Although Cristopher Columbus brought with him a few tobacco leaves and seeds back to Europe, most Europeans didn't get their first taste of the plant until the mid-16th century, when adventurers and diplomats like France's Jean Nicot for whom nicotine is named began to popularize its use