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Microencapsulation functions as a shielding strategy, protecting sensitive compounds from degradation by environmental factors, including oxygen, temperature fluctuations, moisture, enzymes, and gastric acids (288)

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Efpeglenatide is a drug in which an exendin-4 analog is linked to a human immunoglobulin G4 fragment through a polyethylene glycol (PEG linker), allowing for Fc receptor of neonate (FcRn)-mediated recycling and reduced excretion through the kidneys [50]