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Moreover, AmBisome creates a depot inside macrophages that slowly releases the drug in a way that avoids its hemolytic effects and nephrotoxicity (142, 143)

69 Crucially, these effects happen at doses which are inside the normal physiological range for circulating endogenous ghrelin

These initiatives often reflect a broader movement towards creating more livable and sustainable urban environments

Hence, the functionalization of nanoparticles with targeted agents (antibodies, aptamers, antibody-like ligands, peptides and small molecules) with high specificity to SGTP proteins may be a superior alternative to anti-schistosomal treatment to nano-enabled the delivery of anti-schistosomal drugs