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During the apoptotic process, signaling cascades are activated, leading to a controlled death, and avoiding the uncontrolled release of parasites into the surrounding environment ( 2.2 Survival strategies of Leishmania inside macrophages Leishmania has evolved sophisticated ways to resist the array of microbicidal mechanisms generated by the macrophage, namely the oxidative stress, the recruitment of other immune cells and the process of apoptosis

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Refrigerate promptly, keep them out of light, and minimize freeze-thaw cycles once reconstituted

Similar content being viewed by others Introduction From December 2019 on, the outbreak of the novel Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) caused a pandemic with dramatic health-related and socioeconomic consequences