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Materials and methods Post-mortem brain samples Frozen post-mortem tissues were obtained from the NICHD Brain and Tissue Bank for Developmental Disorders at the University of Maryland, Baltimore, MD, USA, and from the Autism Tissue Program at the Harvard Brain Tissue Resource Center, Belmont, MA, USA

Cell compartment-specific, roGFPs, visualized via a fluorescence microscope or CLSM, indicate the in vivo redox state of glutathione in mitochondria, chloroplasts, the cytosol, peroxisomes (primarily GSH) and the endoplasmic reticulum (ER

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