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It Concentrates Where You Need It Most Once absorbed, ergothioneine is transported via OCTN1 and concentrates in tissues most vulnerable to oxidative stress: Erythrocytes (red blood cells) Eye lens Liver and kidney Brain (particularly mitochondria and nucleus) Skin Bone marrow and semen This preferential accumulation in stress-vulnerable tissues strongly supports its protective role

As a spore-former, it is inherently shelf-stable and designed to survive gastric acid transit

Autoimmune diseases of the skin system As the largest organ of the human body, the skin forms a mechanical and immune barrier against the environment

The hormone breaks down quickly in the body, limiting its therapeutic potential in native form