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3.3 Managing abnormal lipid profiles in DKD Dyslipidemia is a significant modifiable risk factor for cardiovascular disease in patients with DKD, and its effective management is essential to reduce overall morbidity and mortality (147)

Images were captured using a confocal laser-scanning microscope to assess NF-B p65 nuclear translocation

Since VIP is ineffective at stimulating gland secretion in CF, then it seems an unlikely candidate to mediate the increased muc5B concentrations (which is largely expressed in the glands and to a lesser extent in surface goblet cells [134]) that are observed during CF exacerbations [135]