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Chen Y, Yang Y, Miller ML, Shen D, Shertzer HG, Stringer KF, Wang B, Schneider SN, Nebert DW, Dalton TP (May 2007)

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B 0 is the baseline motor score, E max is the maximum inhibitory effect, Cp is the apomorphine plasma concentration predicted by the PK model, Ce is the drug concentration at the site of action, EC 50 is the drug concentration that causes 50% of the maximum effect, g is the Hills sigmoid coefficient, and k e0 is the first-order plasma-effect-site equilibration rate constant