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This is because Kla requires the participation of specific enzymes, whose activity is regulated by numerous factors

While we maintain CMS' authority to conduct additional review and make resulting corrections at any time during the wage index development process, in accordance with the policy finalized in the FY 2018 IPPS/LTCH PPS final rule (82 FR 38154 through 38156) and as first implemented with the FY 2019 wage index (83 FR 41389), hospitals are able to request further review of a correction made by CMS that did not arise from a hospital's request for a wage index data correction

J Exp Bot 66:28392856 Yabuta Y, Maruta T, Nakamura A, Mieda T, Yoshimura K, Ishikawa T, Shigeoka S (2008) Conversion of L-galactono-1,4-lactone to L-ascorbate is regulated by the photosynthetic electron transport chain in Arabidopsis