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Int Psychogeriatr 2016;9:116

Effects of topical creams containing vitamin C, a copper-binding peptide cream and melatonin compared with tretinoin on the ultrastructure of normal skin-A pilot clinical, histologic, and ultrastructural study

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Key mechanisms identified in published laboratory research include: Copper chaperone activity: This compound acts as a copper transport molecule in research models, delivering Cu(II) ions to copper-dependent enzymes, including lysyl oxidase (involved in collagen and elastin crosslinking) and superoxide dismutase (a key antioxidant enzyme)