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Further, the time course of these effects on immune function coincided with the observed increases in PBMC GSH content

By contrast, higher PTM concentrations (50%) induced substantial cell death in LLC cells (80.21 10.52%) and 4T1 cells (65.56 8.20%) as well as in DCs (45.23 5.21%), although cell death in DCs was at a significantly lower level than that induced in LLC cells

As a key coenzyme in mitochondrial energy metabolism, increased NAD enhances mitochondrial oxidative phosphorylation, promotes triglyceride breakdown in adipocytes, and converts fat into energy for the body, thereby reducing adipose tissue accumulation

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