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BMO Capital Markets analysts expect a slow launch, however, writing in a note to investors about challenges including a black box warning for risk of acute adrenal insufficiency or adrenal crisis with inadequate concomitant glucocorticoid therapy. The firm said it anticipates broad commercial access will not happen until the second half of 2025

In adults, highly activated osteoclasts in bone tissue can induce arthritis and osteoporosis through bone absorption and inflammation (Lee et al., 2017)