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Histamine flows in from multiple sources: Pollen-triggered mast cell release Stress-triggered mast cell activation Histamine in food (aged cheese, fermented foods, leftover meat) Histamine produced by gut bacteria Other immune triggers (infections, exercise, temperature changes) At the bottom of the bucket, DAO and HNMT act as drains

Effect of Shiftwork on Systemic Markers of Inflammation

Schneeberger, H

119 These findings indicate that obesity contributes to the attainment of the senescent cell burden threshold, potentially contributing to the progression of various chronic diseases associated with aging and obesity