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Understanding Vitamin B12 Deficiency Vitamin B12 deficiency occurs when your body lacks enough of this essential nutrient, leading to symptoms like: Persistent fatigue Weakness and lightheadedness Numbness or tingling in hands and feet Memory problems and difficulty concentrating Mood changes, including irritability and depression Certain factors increase your risk, such as age, certain medications, digestive conditions, and restrictive diets

The muscle-sparing effect represents a significant advantage for body recomposition goals

They may also be necessary when certain medications interfere with B12 absorption or in any other diagnosed condition specifically impacting B12 uptake

They are usually safe but can cause problems for some people