krlec, K., Ruman, R., Jarc, E., Sikiri, P., vajger, U., Petan, T., Perii Nanut, M., trukelj, B., & Berlec, A
95,116 Beyond mitochondria and the NOX family, a variety of enzymes including xanthine oxidase (XO), NOS, lipoxygenase and cytochromes P450 (CYP) can all produce ROS using NAD(P)H as electron donor
This intermediate donates the lactyl group through a non-enzymatic reaction (Rabbani et al., 2014)
There are many reports that describe the in vitro production of endodermal cell types from hPSCs: thymic epithelial cells 26,27,28 , pancreatic beta cells 29 , lung epithelial cells 30 , intestinal cells 31 , cholangiocytes 32,33,34,35 and hepatocytes 3,5,6,11,36,37,38