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The main objective of this clinical trial is to determine the efficacy of 10 weeks personalized dosing of the nicotine patch in motivated smokers unable to quit during the first 2 weeks of standard-dose patch use (21 mg)

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Considerations: Nicotine Absorption: Vaping devices, especially those using nicotine salts like Lost Mary, provide a smoother throat hit, allowing for higher nicotine concentrations without the harshness associated with freebase nicotine