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As described by the 3rd century historian Diogenes Laertius, sooner than trample on it [i.e., a bean field], he endured to be slain at the cross-roads by the men of Acragas. Modern reports of favism date from the mid-19th century when some G6PD-deficient patients presented with jaundice

Deficits in glutathione have been implicated in aging and a host of diseases including Alzheimer's disease, Parkinson's disease, cardiovascular disease, cancer, Down syndrome and autism

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After treatment by phytoestrogens, demethylation of GSTP1, and EPHB2 promoter regions was observed and an increase in their protein expression levels was demonstrated by immunohistochemistry