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AOD-9604 Research Protocols & Administration Dosing in Published Research Research investigations have employed diverse AOD-9604 doses across species and administration routes: Rodent studies: 250-500 mcg/kg orally or intraperitoneally was most common for obesity research Rabbit models: 0.25 mg per joint for osteoarthritis studies (intra-articular injection) Pig pharmacokinetic studies: 1.5 mg/kg IV and 2 mg/kg oral for metabolism characterization Human clinical trials: Oral doses of 0.25-10 mg daily

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Supplies needed for injecting Vitamin B12 and B-Complex 23-25 gauge needle, 1- 1 length for Intramuscular Injection Your healthcare professional will instruct per your body type and injection location

Subsequent elevations in NAD+ levels activate sirtuin 1 (SIRT1), a cellular regulatory enzyme dependent on NAD+ availability