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Its gastric origin contributes to its unusual stability in acidic conditions

Outcomes would be measured with validated instruments: instrumental elasticity and firmness, corneometry and cutometry, standardized photography with blinded grading, and, most convincingly, dermal biopsies quantifying collagen density and organization before and after

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GPx activity ( Supplementary Figure 3A ) maintained at the baseline level until 1 week after LPS administration and ended the trial with the maximum value, whereas SOD activity ( Supplementary Figure 3B ) remained stable throughout the experiment