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Back to Journals Clinical, Cosmetic and Investigational Dermatology Volume 15 Factors Influencing Skin Aging and the Important Role of Estrogens and Selective Estrogen Receptor Modulators (SERMs) Authors Lephart ED , Naftolin F Received 5 June 2022 Accepted for publication 19 July 2022 Published 19 August 2022 Volume 2022:15 Pages 16951709 DOI Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 4 Editor who approved publication: Dr Jeffrey Weinberg Edwin D Lephart, 1 Frederick Naftolin 2 1 Department of Cell Biology, Physiology and The Neuroscience Center, Brigham Young University, Provo, UT, USA

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Although FOXO4s specific effects on mitochondria are as direct as the other peptides above, it is known to regulate the expression of genes involved in oxidative stress response and energy metabolism, which can impact mitochondrial function indirectly (Liu, 2019)

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Laboratory findings suggest TB-500 could engage with the globular form of actin (G-actin) and potentially reduce its polymerization into filamentous actin (F-actin)

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Zinc (Zn) is a vital trace element that has anti-inflammatory and antioxidant effects and is involved in numerous biological processes (Haase et al

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