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Traditional obesity intervention strategies (e.g., dietary control, exercise, conventional weightloss drugs) are often limited by slow onset, obvious side effects, and high rebound rates, and can hardly fundamentally reverse the abnormal metabolic phenotype of adipose tissue

Note: this is not the same as having a metallic taste in your mouth, which can be a sign of vitamin B12 deficiency

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It is important to highlight that CSF2 and CXCL10 encode pro-inflammatory proteins linked to neurodegenerative diseases 51,52,53 , and, as mentioned above, elevated levels of CXCL10 protein are associated with persistent VCD in individuals from the same cohort of the present study 20