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Nat Rev Dis Primers 6(1):123 [DOI] [PubMed] [Google Scholar] De Sanctis V, Soliman AT, Canatan D, Yassin MA, Daar S, Elsedfy H, Di Maio S, Raiola G, Corrons J-LV, Kattamis C (2019) Thyroid disorders in homozygous -thalassemia: current knowledge, emerging issues and open problems