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Germinal centers can form within the thyroid tissue of affected individuals, exacerbating the autoimmune response and causing further inflammation (Weetman, 2000)

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Delta Sleep-Inducing Peptide (DSIP) is a naturally occurring neuropeptide classified as a nonapeptide, being composed of nine amino acids with the sequence Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu