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Causes of CD, include Alzheimers disease, degenerative diseases, vascular dementia, certain types of drug abuse, depression, anxiety, disturbed sleep, hormones, metabolic disorders, diabetes mellitus, alcohol abuse, Lyme disease, hippocampal sclerosis, subdual and epidural hematomas, vitamin B12 deficiency, seizures, HIV-associated neurocognitive disorder, and Hashimotos encephalopathy

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Adigun RA, Malan FP, Balogun MO, October N (2022) Rational optimization of dihydropyrimidinonequinoline hybrids as Plasmodium falciparum glutathione reductase inhibitors