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But it requires methyl molecules, which are often in low supply (modern life is full of toxins), especially in folks suffering from B12 deficiency or pernicious anemia

Similarly, if you use proton pump inhibitors or H2 receptor antagonists for acid reflux or peptic ulcers, your stomach acid levels may decrease, making it harder for your body to absorb B12 from your diet

This increase in red blood cells can help with muscle weakness, too, since it allows the tissue to recover from exertion much more rapidly

This is the default starting point for most researchers and the dose with the best track record in community protocols