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FIGURE 7 7 Discussion 7.1 Limits of preclinical models and translational relevance While a growing body of preclinical evidence supports the therapeutic potential of redox-targeted antioxidants and stem cellderived EVs in mitigating oxidative stress and restoring ovarian function, significant translational hurdles remain before these strategies can be applied clinically in women

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Liraglutide is a prominent GLP-1RA that can attain total body weight losses and lean mass preservation

Diaz-Thomas A, Shulman D: Use of aromatase inhibitors in children and adolescents: whats new