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The animals were then deeply anesthetized with 3% isoflurane and 50 mg/kg of ketamine followed by a laminectomy at lumbar level L2-L3, corresponding to the sacrocaudal spinal cord

Activity-dependent gene transcription and mRNA translation Neuronal activity regulates gene transcription and mRNA translation in a dynamic manner

The resulting construct, which is produced commercially in a Chinese hamster ovary cell line, is fully human, although the hinge region is not naturally occurring and potentially antigenic