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This selective mechanism produces metabolic safety benefits that may make AOD-9604 appropriate for individuals who cannot tolerate or have contraindications to conventional growth hormone therapy

The size of these linesoften several feet in diameter and dozens of feet longexacerbates the problem by holding large volumes of water at relatively warm temperatures

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All are serine esterases that harbor a common structural elementthe alpha/beta-hydrolase foldand a conserved catalytic diad or triad that is composed of the G X S X G pentapeptide motif as well as an active aspartate or glutamate (D/E)GG tripeptide and an active histidine (H)