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Duffy, J

It is worth noting that a previous study has already reported that QCT exhibits strong affinity and stability towards EGFR and AKT1, two key targets of QCT, and inhibits the EGFR/AKT pathway

We asked if we could exploit the fact that NAPstars encompass a Rex dimer within one polypeptide, by introducing a blend of two different Rex domains into one NAPstar sensor, with the aim to expand the range of accessible NADP redox states