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KM8094 effectively inhibits Gln uptake, induces antibody-dependent cytotoxicity in GC cells in vitro, and inhibits the growth of various GC cell-transplanted tumors in vivo [76]

In this way, the PGE 2 -Cav1.3-PARP1 axis forms a self-reinforcing survival pathway in which inflammation promotes Ca 2+ influx, and Ca 2+ influx supports anti-apoptotic signaling, allowing ectopic cells to evade clearance and persist in hostile microenvironments ( Therefore, targeting Ca 2+ signaling, particularly Cav1.3, may represent a dual therapeutic strategy by restoring mitochondrial resilience while also normalizing uterine contractility and pain-related signaling

Superoxide dismutase a front-line antioxidant enzyme shuts down

Mahasudarshan is a bitter, detoxifying, and immune-modulating herb was added because it helps reduce systemic inflammation, improve liver detoxification, and strengthen immunity