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2.3 PYC metabolism and gut microbiota PYC is derived from French coastal pine bark extract and is standardized to contain 70 5% proanthocyanidins, consisting of catechin and epicatechin polymers with different chain lengths, as well as low molecular weight compounds containing paclitaxel, vanillic acid, gallic acid, cinnamic acid, ferulic acid, and caffeic acid ( Figure 1 ) ( Akkermansia muciniphila and butyrate-producing bacteria showed increased colonisation while inhibiting LPS-producing bacteria ( Bacteroidota , scillospiraceae , Muribaculaceae and Desulfovibrionaceae , as well as activate short-chain fatty acids (SCFAs) receptors in the colon ( Lactobacillus plantarum and Acetobacter pomorum ( Wu et al., 2025)
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tetrahedral, 1 Structures of Metal Complexes The coordination numbers of metal ions in metal complexes can range from 2 to at least 9