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Cells in different environmental conditions release exosomes with diverse cargo, complicating the predictability of cell-derived exosome therapies (262)

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Stress, Cortisol, and Oxidative Burden Chronic psychological stress elevates cortisol and other stress hormones, which increase oxidative stress through multiple mechanisms including promotion of inflammatory cytokine production, impairment of antioxidant enzyme function, increased metabolic rate and oxygen consumption, and disruption of sleep and other restorative processes