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Researchers observed that GHK-Cu influences expression of over 4,000 human genes based on microarray studies, with significant effects on genes involved in collagen synthesis, metalloproteinase regulation, antioxidant defense (SOD, glutathione), and growth factor signaling (TGF-, VEGF, FGF)

Comprehensive analysis of the expression of SLC30A family genes and prognosis in human gastric cancer

5 combined L-BSO with sulphasalazine or auranofin (a gold salt used in the treatment of rheumatoid arthritis) to inhibit both glutathione- and thioredoxin-dependent antioxidant pathways, triggering synergistic cancer cell death (Fig